Sputnik V, Sputnik Light will be able to neutralize Omicron, says RDIF

According to the Gamaleya Institute, the Russian COVID-19 vaccines Sputnik V and Sputnik Light are predicted to neutralise the novel coronavirus strain Omicron.

The Gamaleya Institute believes that both Sputnik V and Sputnik Light will neutralise the current Omicron variant, according to Kirill Dmitriev, CEO of the Russian Direct Investment Fund (RDIF).

According to Kirill Dmitriev, the Gamaleya Institute has already began producing a new version of the Sputnik vaccine suited to Omicron, based on current methods for developing vaccination versions for variants of concern as soon as possible.

In the unusual event that such a change is required, the new Sputnik Omicron version can be ready for mass manufacturing in 45 days, he noted.

“The Gamaleya Institute believes that Sputnik V and Sputnik Light will neutralise Omicron as they have the highest efficacy against other mutations. In an unlikely case a modification is needed, we will provide several Sputnik Omicron boosters by February 20, 2022,” said Dmitriev.

The Russian Sputnik V and Sputnik Light vaccines have proven to be highly effective against all variants of SARC-Cov-2 known to date. The RDIF said that Sputnik vaccine’s efficacy is based on the heterogeneous boosting approach using two different vectors for two shots, pioneered by the Gamaleya Institute, and a proven adenoviral vector platform, which triggers a broader immune response as compared to mRNA vaccines.

The B.1.1.529 variant, named Omicron, was first reported to WHO from South Africa on November 24. The global health body said on Monday that Omicron is a highly divergent variant with a high number of mutations, including 26-32 in the spike, some of which are concerning and may be associated with immune escape potential and higher transmissibility. However, there are still considerable uncertainties, added the global health body.