Pfizer starts phase-III clinical trial in adults for investigational vaccine against RSV

Pfizer recently announced the initiation of RENOIR (RSV vaccine Efficacy study iNOlder adults Immunised against RSV disease), a phase-III clinical trial evaluating the efficacy, immunogenicity and safety of a single dose of its respiratory syncytial virus (RSV) bivalent prefusion F subunit investigational vaccine candidate (RSVpreF) in adults aged 60 years or older.

Speaking in this regard, Kathrin U Jansen, PhD, Senior Vice President and Head, Vaccine Research and Development, Pfizer, said, “RSV is a significant cause of severe respiratory disease in older adults, and it can cause disability and death. There is an important unmet medical need for an effective vaccine that can help protect older adults against this highly-contagious disease. The start of this phase-III study is an important step forward towards our goal of comprehensive immunisation against RSV disease, which includes developing a potential first vaccine to help prevent RSV disease in adults as well as the ongoing efforts to help protect infants through maternal immunisation, subject to regulatory approval of the candidate vaccine.”

The phase-III RENOIR trial of RSVpreF is a global, randomised, double-blind, placebo-controlled study that expects to enroll approximately 30,000 participants aged 60 years and older. The primary objectives of the study will assess safety and efficacy for the prevention of moderate-to-severe lower respiratory tract illness (msLRTI-RSV) during the first RSV season, added the statement.

Medically Speaking Team

Recent Posts

ANTIBIOTIC MISUSE IN INDIA: HOW IT’S MAKING INFECTION TREATMENT MORE CHALLENGING

Antibiotic use has surged globally, leading to a rise in antibiotic resistance, especially concerning in…

11 hours ago

CHILD DIES FROM CHOKING ON CANDY: HOW TO SAFEGUARD AGAINST CHOKING HAZARDS IN YOUNG CHILDREN

Choking is a leading cause of injury and death in young children, particularly those under…

12 hours ago

Video: How Hard Water Leads to Hair Fall and Expert Tips to Combat It

Hard Water (Khara Pani) Leading To Hair Fall Hard water is rich in minerals and…

14 hours ago

“How High Blood Pressure During Pregnancy Is Rising: What Every Expectant Mother Should Know”

Discover how the rise in high blood pressure during pregnancy is impacting maternal and fetal…

14 hours ago

“Revitalize Your Weight Loss Journey: 6 Powerful Homemade Drinks to Naturally Melt Away Fat!”

"Discover the transformative power of six delicious homemade drinks that can help you naturally melt…

14 hours ago

“Revitalize Your Weight Loss Journey: 8 Powerful Fat-Flushing Drinks to Boost Your Results!”

"Transform your weight loss routine with these eight delicious fat-flushing drinks that not only hydrate…

14 hours ago